Endocrine Abstracts

Introduction: Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a rare congenital cause of primary amenorrhea, characterized by aplasia of the vagina with or without concurrent uterine and/or cervical aplasia. MRKH syndrome has a heavy psychological impact, and requires multidisciplinary management.Case Report: A 17-year-old female patient presented for exploration of a primary amenorrhea. Her medical history was significant for recurrent urinary tr...

Introduction: Epstein-Barr virus (EBV) is a well-known human tumor virus with a very high prevalence in the population, this virus is associated with epithelial and lymphoid malignancies, including lymphoepithelioma carcinoma of thyroid. This subtype of thyroid carcinoma is characterized by histologic features similar to those of undifferentiated carcinoma of the thyroid. Case Report: A 17-year-old male patient, his medical and family histories were non-...

Introduction: Pheochromocytomas are rare neuroendocrine tumors producing catecholamines, they are usually unilateral. However, they can be located bilaterally. They still pose several problems in their diagnosis if they are associated with an adrenal cyst, which is the case in our patient.Case Report: A 34-years-old male patient, his medical and family histories were non specific, admitted to the emergency room for lumbar pain, with no other associated s...

Introduction: Stiff-Person Syndrome (SPS) is a rare autoimmune neurological disorder that can be associated with other autoimmune diseases including type 1 diabetes mellitus (T1DM). The presence of alternative forms of autoimmune diabetes, such as latent autoimmune diabetes in adults (LADA) in SPS, is not well described.Case Report: A 63 years old male patient, his medical and family histories were non-specific. He developed progressive rigidity in trunc...

Introduction: Pituitary stalk interruption syndrome (PSIS) is a distinct developmental defect characterized by a thin or absent pituitary stalk, hypoplasia of the adenohypophysis, and ectopic location of the neurohypophysis.Case report: A 36 years old male patient, full term born by vaginal delivery, with birth asphyxia. Birth weight was 2800 g, length was 51 cm, and no other postnatal events were noticed. Psychomotor milestones were achieved normally. h...

Introduction: Androgen insensitivity syndrome (AIS) is a genetic sexual developmental disorder (DSD) inherited in an X-linked recessive mode, responsible for 30 to 70% of cases of DSD 46, XY. Androgen insensitivity can be complete (CAIS), partial (PAIS) or mild depending on the degree of receptor sensitivity to androgen stimulationCase report: A 17-year-old female patient with a history of inguinal hernia operated in childhood who was admitted for explor...

Background: Cardiovascular stratification and prevention in type 2 diabetic patients represent a major public health preoccupation in order to reduce their mortality. Several methods of detecting atherosclerosis have been developed such as biomarkers. The aim of this study was to evaluate the association between B-type natriuretic peptide (BNP) and cardiovascular risk (CVR) in type 2 diabetic patients.Methods: We conducted a cross-sectional study in 71 t...

Introduction: Cardiovascular diseases are frequent in patients with hypopituitarism receiving conventional hormone replacement therapy. They represent the main cause of premature death in this population. Emerging evidence smggests that beyond traditional risk factors, evaluating coronary calcium score (CCS) and inflammatory markers such as high-sensitivity C-reactive protein (hs-CRP) provides valuable insights into cardiovascular health in this population. The aims of the pre...

Introduction: Sheehan’s syndrome (SS) is characterized by a deficiency in pituitary hormone secretion. It is now being closely inspected for its implication in the onset of metabolic syndrome (MS). The aims of this study were to determine the prevalence of MS and assess its associated factors in women with SS.Methods: We carried out a cross-sectional study involving 50 patients diagnosed with SS and 50 controls, matched for age and body-mass index (...

Introduction: Micronutrients are involved in numerous physiological processes at the cellular level. They play an essential role in the synthesis of neurotransmitters, crucial for the brain’s optimal functioning. The aim of our study was to determine the association between micronutrient intake and brain function in type 2 diabetic patients using a validated questionnaire.Methods: A descriptive analysis was conducted on 115 type 2 diabetics. Each pa...